CNS Targets for multi-functional drugs in the treatment of Alzheimer’s and Parkinson’s diseases

@article{Youdim2004CNSTF,
  title={CNS Targets for multi-functional drugs in the treatment of Alzheimer’s and Parkinson’s diseases},
  author={Moussa B. H. Youdim and Jerry J. Buccafusco},
  journal={Journal of Neural Transmission},
  year={2004},
  volume={112},
  pages={519-537}
}
Patients with mild forms of dementia and age-related memory impairment have just begun to benefit from pharmacotherapy developed over the last several years. However, current approaches do not significantly modify the course of neurodegeneration or of the aging process, and they offer limited and transient benefit to many patients. The goal of this review is to summarize new potential approaches in which molecules have been developed expressly to target multiple brain systems for the treatment… CONTINUE READING

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