CNS Schwann cells display oligodendrocyte precursor-like potassium channel activation and antigenic expression in vitro

@article{Kegler2014CNSSC,
  title={CNS Schwann cells display oligodendrocyte precursor-like potassium channel activation and antigenic expression in vitro},
  author={Kristel Kegler and Ilka Imbschweiler and Reiner Ulrich and Peter Kovermann and Christoph Fahlke and Ulrich Deschl and Arno Kalkuhl and Wolfgang Baumg{\"a}rnter and Konstantin Wewetzer},
  journal={Journal of Neural Transmission},
  year={2014},
  volume={121},
  pages={569-581}
}
Central nervous system (CNS) injury triggers production of myelinating Schwann cells from endogenous oligodendrocyte precursors (OLPs). These CNS Schwann cells may be attractive candidates for novel therapeutic strategies aiming to promote endogenous CNS repair. However, CNS Schwann cells have been so far mainly characterized in situ regarding morphology and marker expression, and it has remained enigmatic whether they display functional properties distinct from peripheral nervous system (PNS… CONTINUE READING
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