CNQX and AMPA inhibit electrical synaptic transmission: A potential interaction between electrical and glutamatergic synapses

@article{Li2008CNQXAA,
  title={CNQX and AMPA inhibit electrical synaptic transmission: A potential interaction between electrical and glutamatergic synapses},
  author={Qin Li and Brian Donald Burrell},
  journal={Brain Research},
  year={2008},
  volume={1228},
  pages={43-57}
}
Electrical synapses play an important role in signaling between neurons and the synaptic connections between many neurons possess both electrical and chemical components. Although modulation of electrical synapses is frequently observed, the cellular processes that mediate such changes have not been studied as thoroughly as plasticity in chemical synapses. In the leech (Hirudo sp), the competitive AMPA receptor antagonist CNQX inhibited transmission at the rectifying electrical synapse of a… CONTINUE READING
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