CMV driven CD8(+) T-cell activation is associated with acute rejection in lung transplantation.

Abstract

Lung transplantation is the definitive treatment for terminal respiratory disease, but the associated mortality rate is high. Acute rejection of the transplanted lung is a key determinant of adverse prognosis. Furthermore, an epidemiological relationship has been established between the occurrence of acute lung rejection and cytomegalovirus infection… (More)
DOI: 10.1016/j.clim.2013.03.012

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@article{Roux2013CMVDC, title={CMV driven CD8(+) T-cell activation is associated with acute rejection in lung transplantation.}, author={Antoine Le Roux and Gis{\'e}le Mourin and Sol{\`e}ne Fastenackels and Jorge R. Almeida and Maria Candela Iglesias and Anders Boyd and Emma Gostick and Martin R Larsen and David A. Price and Karim Sacr{\'e} and Daniel C. Douek and Brigitte Autran and Cl{\'e}ment Picard and Sandra Maria da Rocha Neto de Miranda and Delphine Sauce and Marc J. Stern and Victor Appay}, journal={Clinical immunology}, year={2013}, volume={148 1}, pages={16-26} }