CMV-Specific CD8 T Cell Differentiation and Localization: Implications for Adoptive Therapies

Abstract

Human cytomegalovirus (HCMV) is a ubiquitous virus that causes chronic infection and, thus, is one of the most common infectious complications of immune suppression. Adoptive transfer of HCMV-specific T cells has emerged as an effective method to reduce the risk for HCMV infection and/or reactivation by restoring immunity in transplant recipients. However… (More)
DOI: 10.3389/fimmu.2016.00352

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