CLSI EP17-A protocol: a useful tool for better understanding the low end performance of total prostate-specific antigen assays.

@article{Moretti2011CLSIEP,
  title={CLSI EP17-A protocol: a useful tool for better understanding the low end performance of total prostate-specific antigen assays.},
  author={Marco Moretti and Davide Sisti and Marco B. L. Rocchi and Ernesto Delprete},
  journal={Clinica chimica acta; international journal of clinical chemistry},
  year={2011},
  volume={412 11-12},
  pages={1143-5}
}
BACKGROUND Clinical Laboratory and Standards Institute (CLSI) published EP17-A guideline, recommending new definitions for low end performances: Limit of Blank (LoB), Limit of Detection (LoD) and Limit of Quantitation (LoQ). The aim of this study was to determine LoB, LoD and LoQ by applying EP17-A to Hybritech and World Health Organization (WHO) calibrated Access Total PSA assays, and verify the correlation between results generated by the same reagent with both calibrations, particularly at… CONTINUE READING