Clozapine and the risk of haematological malignancies - Authors' reply.
- MedicineThe lancet. Psychiatry
A CLOZAPINE'S UNCHARTED VOYAGE: FIVE YEARS AND A PANDEMIC AFTER THE END OF MANDATORY HAEMATOLOGICAL NOTIFICATIONS TO THE SPANISH MEDICINES AGENCY
- MedicineRevista de Psiquiatría y Salud Mental
Long-term treatment with clozapine and other antipsychotic drugs and the risk of haematological malignancies in people with schizophrenia: a nationwide case-control and cohort study in Finland.
- Medicine, PsychologyThe lancet. Psychiatry
From the Second Half of the Twentieth Century to the Early Twenty-First: The Psychopharmacologic Era
Clozapine-associated myocarditis in the World Health Organization's pharmacovigilance database: Focus on reports from various countries
- MedicineRevista de psiquiatria y salud mental
History of Antipsychotics
Genetic risk of clozapine-induced leukopenia and neutropenia: a genome-wide association study
- MedicineTranslational Psychiatry
A genome-wide association study in a Chinese population provides novel and valuable understanding of the genetic and immune causes of CIL and CIN, which is useful for improving clinical management of clozapine related treatment for schizophrenia.
Dopamine and Response to Antipsychotic Medication
- PsychologyPET and SPECT in Psychiatry
Clozapine: An Updated Overview of Pharmacogenetic Biomarkers, Risks, and Safety—Particularities in the Context of COVID-19
- Medicine, PsychologyBrain sciences
Clozapine doses should be personalized for each patient based on pharmacogenetics testing when available and the genetic vulnerability postulates predictors of adverse reactions’ severity; patients with a lower genetic risk could have less frequent hematological monitoring.
Neutrophil fluorescence in clozapine users is attributable to a 14kDa secretable protein
- Biology, MedicinePharmacology research & perspectives
Clozapine‐associated fluorescence in neutrophils is originating from a 14kDa soluble protein (fragment) present in azurophilic granules of neutrophil, and the identity of this protein and its potential role in the pathophysiology of clozAPine‐induced agranulocytosis is explored.
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- MedicineNursing mirror and midwives journal
Of 41 cases of acute paracetamol poisoning one died of gastrointestinal haemorrhage and acute massive necrosis of the liver, three became jaundiced, and 13 others had biochemical evidence of…
Acute liver necrosis following overdose of paracetamol.
- MedicineBritish medical journal
A woman aged 30, an inmate of a mental institution, was admitted to hospital two hours after ingesting at least 50 paracetamol tablets, and gastric lavage was carried out almost immediately.