CLOZAPINE AND AGRANULOCYTOSIS

@article{IdnpnHeikkil1975CLOZAPINEAA,
  title={CLOZAPINE AND AGRANULOCYTOSIS},
  author={Juhana E. Id{\"a}np{\"a}{\"a}n-Heikkil{\"a} and Eeva Alhava and Martti Olkinuora and Ilmari Palva},
  journal={The Lancet},
  year={1975},
  volume={306}
}
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108 Citations
Background Citations
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108 Citations

Clozapine and the risk of haematological malignancies - Authors' reply.

A CLOZAPINE'S UNCHARTED VOYAGE: FIVE YEARS AND A PANDEMIC AFTER THE END OF MANDATORY HAEMATOLOGICAL NOTIFICATIONS TO THE SPANISH MEDICINES AGENCY

Long-term treatment with clozapine and other antipsychotic drugs and the risk of haematological malignancies in people with schizophrenia: a nationwide case-control and cohort study in Finland.

From the Second Half of the Twentieth Century to the Early Twenty-First: The Psychopharmacologic Era

Clozapine-associated myocarditis in the World Health Organization's pharmacovigilance database: Focus on reports from various countries

History of Antipsychotics

Genetic risk of clozapine-induced leukopenia and neutropenia: a genome-wide association study

A genome-wide association study in a Chinese population provides novel and valuable understanding of the genetic and immune causes of CIL and CIN, which is useful for improving clinical management of clozapine related treatment for schizophrenia.

Dopamine and Response to Antipsychotic Medication

Clozapine: An Updated Overview of Pharmacogenetic Biomarkers, Risks, and Safety—Particularities in the Context of COVID-19

Clozapine doses should be personalized for each patient based on pharmacogenetics testing when available and the genetic vulnerability postulates predictors of adverse reactions’ severity; patients with a lower genetic risk could have less frequent hematological monitoring.

Neutrophil fluorescence in clozapine users is attributable to a 14kDa secretable protein

Clozapine‐associated fluorescence in neutrophils is originating from a 14kDa soluble protein (fragment) present in azurophilic granules of neutrophil, and the identity of this protein and its potential role in the pathophysiology of clozAPine‐induced agranulocytosis is explored.
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