CLOSTRIDIUM DIFFICILE AND THE ÆTIOLOGY OF PSEUDOMEMBRANOUS COLITIS

@article{Larson1978CLOSTRIDIUMDA,
  title={CLOSTRIDIUM DIFFICILE AND THE {\aE}TIOLOGY OF PSEUDOMEMBRANOUS COLITIS},
  author={H. Larson and A. Price and P. Honour and S. Borriello},
  journal={The Lancet},
  year={1978},
  volume={311},
  pages={1063-1066}
}
Bacterial isolates from 5 patients with pseudomembranous colitis (P.M.C.) were screened for toxin production. Strains of Clostridium from 4 patients produced in vitro a toxin similar to that found in P.M.C. faecal suspension. These were identified as C. difficile. Use of the strains from 2 patients induced a fatal enterocolitis when inoculated orally into hamsters pretreated with vancomycin. The C. difficile that produced the toxin in vitro was then re-isolated from hamster caecal contents… Expand
Pseudomembranous colitis is an infection
Clostridium difficile colitis.
Epidemiology of experimental enterocecitis due to Clostridium difficile.
Antibiotic-associated pseudomembranous colitis.
Colitis induced by Clostridium difficile.
Pseudomembranous (antibiotic-associated) colitis.
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