CLINICAL AND ECONOMIC CONSEQUENCES OF WOUND SEPSIS AFTER APPENDICECTOMY AND THEIR MODIFICATION BY METRONIDAZOLE OR POVIDONE IODINE

@article{Foster1981CLINICALAE,
  title={CLINICAL AND ECONOMIC CONSEQUENCES OF WOUND SEPSIS AFTER APPENDICECTOMY AND THEIR MODIFICATION BY METRONIDAZOLE OR POVIDONE IODINE},
  author={Glennis Elmore Foster and J. B. Bourke and J S Bolwell and Justin Doran and Timothy H. W. Balfour and A D Holliday and Jack D Hardcastle and D. P. Marshall},
  journal={The Lancet},
  year={1981},
  volume={317},
  pages={769-771}
}
The effects of intrarectal metronidazole and intraincisional povidone iodine on sepsis after emergency appendicectomy were compared in a double-blind randomised controlled trial in 496 patients. Wound sepsis occurred in 12.3% of metronidazole-treated patients compared with 24% in the povidone-iodine group and 23.5% in an untreated control group. The metronidazole-treated patients left hospital approximately 2 days earlier than patients in the other two groups. They returned to work sooner and… CONTINUE READING

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