CLEARANCE TIMES OF PORPHYRIN DERIVATIVES FROM MICE AS MEASURED BY in vivo FLUORESCENCE SPECTROSCOPY

@article{Kennedy1992CLEARANCETO,
  title={CLEARANCE TIMES OF PORPHYRIN DERIVATIVES FROM MICE AS MEASURED BY in vivo FLUORESCENCE SPECTROSCOPY},
  author={James C. Kennedy and Pierre Nadeau and Z. J. Petryka4 and R. H. Porrier and Glenn E. Weagle},
  journal={Photochemistry and Photobiology},
  year={1992},
  volume={55}
}
Abstract— The clearance times of 17 different porphyrin derivatives from SKH:HR‐1 mice have been measured using the technique of in vivo fluorescence spectroscopy. This technique monitors the in vivo porphyrin fluorescence observed from the external skin surface. Most hydrophilic porphyrin derivatives show relatively short clearance times, in the order of 2.5–6 h. The dicarboxylic acid porphyrins, proto‐, hydroxyethylvinyldeutero‐and hematoporphyrin IX have clearance times of 7.8, 12.2 and 14.7… 
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CONTINUOUS, NONINVASIVE MEASUREMENT OF In Vivo pH IN CONSCIOUS MICE
TLDR
Extracellular pH was measured continuously and noninvasively in hairless mice using a transcutaneous spectronuorometric technique and a fluorescent pH probe, bis‐carboxyethyl carboxyfluorescein (BCECF) using an optical fiber system and a photomultiplier tube.

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