CLASSIC: Consistent Longitudinal Alignment and Segmentation for Serial Image Computing
@article{Xue2005CLASSICCL,
title={CLASSIC: Consistent Longitudinal Alignment and Segmentation for Serial Image Computing},
author={Zhong Xue and Dinggang Shen and Christos Davatzikos},
journal={Information processing in medical imaging : proceedings of the ... conference},
year={2005},
volume={19},
pages={
101-13
}
}This paper proposes a temporally-consistent and spatially-adaptive longitudinal MR brain image segmentation algorithm, referred to as CLASSIC, which aims at obtaining accurate measurements of rates of change of regional and global brain volumes from serial MR images. The algorithm incorporates image-adaptive clustering, spatiotemporal smoothness constraints, and image warping to jointly segment a series of 3-D MR brain images of the same subject that might be undergoing changes due to…
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References
SHOWING 1-10 OF 29 REFERENCES
Measuring temporal morphological changes robustly in brain MR images via 4-dimensional template warping
- Materials ScienceNeuroImage
- 2004
The boundary shift integral: an accurate and robust measure of cerebral volume changes from registered repeat MRI
- BiologyIEEE Transactions on Medical Imaging
- 1997
The BSI is an accurate and robust measure of regional and global cerebral volume changes and good linear correlation was obtained between the ventricular BSI and the difference in their segmented volumes.
An image-processing system for qualitative and quantitative volumetric analysis of brain images.
- MedicineJournal of computer assisted tomography
- 1998
This image-processing system has sufficient accuracy for longitudinal imaging data and is currently being used in the analysis of neuroimaging data of the Baltimore Longitudinal Study of Aging.
Simulation of tissue atrophy using a topology preserving transformation model
- Computer ScienceIEEE Transactions on Medical Imaging
- 2006
A dense warping deformation is found that produces the corresponding levels of volumetric loss on the labeled tissue using an energy minimization strategy and provides exact correspondences between images prior and posterior to the atrophy.
Estimating the bias field of MR images
- Computer ScienceIEEE Transactions on Medical Imaging
- 1997
The authors show that replacing the class other, which includes all tissue not modeled explicitly by Gaussians with small variance, by a uniform probability density, and amending the expectation-maximization (EM) algorithm appropriately, gives significantly better results.
Segmentation of MR Brain Images into Cerebrospinal Fluid Spaces, White and Gray Matter
- MedicineJournal of computer assisted tomography
- 1989
An interactive computer method for quantifying CSF, white matter, and gray matter in magnetic resonance (MR) axial brain scans is presented and the gray/white ratios compare favorably with those determined in a published postmortem brain study.
A modified fuzzy c-means algorithm for bias field estimation and segmentation of MRI data
- Computer ScienceIEEE Transactions on Medical Imaging
- 2002
A novel algorithm for fuzzy segmentation of magnetic resonance imaging (MRI) data and estimation of intensity inhomogeneities using fuzzy logic and the neighborhood effect acts as a regularizer and biases the solution toward piecewise-homogeneous labelings.
New variants of a method of MRI scale standardization
- MedicineIEEE Transactions on Medical Imaging
- 2000
New variants of this standardizing method can help to overcome some of the problems with the original method and extraction of quantitative information about healthy organs or about abnormalities can be considerably simplified.
HAMMER: hierarchical attribute matching mechanism for elastic registration
- Computer ScienceIEEE Transactions on Medical Imaging
- 2002
A new approach is presented for elastic registration of medical images, and is applied to magnetic resonance images of the brain, where it results in accurate superposition of image data from individuals with significant anatomical differences.
Estimation of CSF, white and gray matter volumes in hydrocephalic children using fuzzy clustering of MR images.
- MedicineComputerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
- 1994















