CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors.

Abstract

BACKGROUND The scavenger receptors are cell-surface receptors for native and modified lipoproteins that play a critical role in the accumulation of lipids by macrophages. CLA-1/SR-BI binds HDL with high affinity and is involved in the cholesterol reverse-transport pathway. Peroxisome proliferator-activated receptors (PPARs) are transcription factors… (More)

Topics

7 Figures and Tables

Cite this paper

@article{Chinetti2000CLA1SRBIIE, title={CLA-1/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors.}, author={Guiletta Chinetti and Fernand Gbaguidi and Sabine Griglio and Ziad Mallat and Michela Antonucci and Pierre Poulain and J. Chapman and Jamila Fruchart and Alain Tedgui and Jamila Najib-Fruchart and Bart Staels}, journal={Circulation}, year={2000}, volume={101 20}, pages={2411-7} }