CK2: a protein kinase in need of control.

  title={CK2: a protein kinase in need of control.},
  author={Barbara Guerra and Brigitte S Boldyreff and Stefania Sarno and Luca Cesaro and Olaf Georg Issinger and Lorenzo A Pinna},
  journal={Pharmacology & therapeutics},
  volume={82 2-3},
Protein kinase CK2 is a heterotetrameric alpha2beta2 Ser/Thr protein kinase with some features unusual among the eukaryotic protein kinases: (1) CK2 recognizes phosphoacceptor sites specified by several acidic determinants; (2) CK2 can use both ATP and GTP as phosphoryl donors; and (3) the regulatory properties of CK2 are poorly understood; it is… CONTINUE READING