CISA: Contig Integrator for Sequence Assembly of Bacterial Genomes

  title={CISA: Contig Integrator for Sequence Assembly of Bacterial Genomes},
  author={Shin-Hung Lin and Yu-Chieh Liao},
  booktitle={PloS one},
A plethora of algorithmic assemblers have been proposed for the de novo assembly of genomes, however, no individual assembler guarantees the optimal assembly for diverse species. Optimizing various parameters in an assembler is often performed in order to generate the most optimal assembly. However, few efforts have been pursued to take advantage of multiple assemblies to yield an assembly of high accuracy. In this study, we employ various state-of-the-art assemblers to generate different sets… CONTINUE READING
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