CIITA activates the expression of MHC class II genes in mouse T cells.

Abstract

It has long been a puzzle that MHC class II molecules are expressed in human T cells after activation but not in mouse T cells; this expression is believed to play a role in the cell mediated immune response. Recently the MHC class II transactivator (CIITA) has been reported to be a major regulatory factor for both the constitutive and IFN inducible… (More)

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@article{Chang1995CIITAAT, title={CIITA activates the expression of MHC class II genes in mouse T cells.}, author={C. H. Chang and S C Hong and Christopher Hughes and Charles A. Janeway and Robert Flavell}, journal={International immunology}, year={1995}, volume={7 9}, pages={1515-8} }