CHIP mediates down-regulation of nucleobindin-1 in preosteoblast cell line models.


Nucleobindin-1 (NUCB1), also known as Calnuc, is a highly conserved, multifunctional protein widely expressed in tissues and cells. It contains two EF-hand motifs which have been shown to play a crucial role in binding Ca(2+) ions. In this study, we applied comparative two-dimensional gel electrophoresis to characterize differentially expressed proteins in… (More)
DOI: 10.1016/j.cellsig.2016.04.016


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