CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality

@inproceedings{Hoffmeister2017CHD3AC,
  title={CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality},
  author={Helen Andrea Hoffmeister and Andreas Fuchs and Fabian Erdel and Sophia Charlotte Pinz and Regina Groebner-Ferreira and Astrid Bruckmann and Rainer Deutzmann and Uwe Schwartz and Rodrigo D{\'i}az Maldonado and Claudia Huber and Anne-Sarah Dendorfer and Karsten Rippe and Gernot L{\"a}ngst},
  booktitle={Nucleic acids research},
  year={2017}
}
CHD3 and CHD4 (Chromodomain Helicase DNA binding protein), two highly similar representatives of the Mi-2 subfamily of SF2 helicases, are coexpressed in many cell lines and tissues and have been reported to act as the motor subunit of the NuRD complex (nucleosome remodeling and deacetylase activities). Besides CHD proteins, NuRD contains several repressors like HDAC1/2, MTA2/3 and MBD2/3, arguing for a role as a transcriptional repressor. However, the subunit composition varies among cell- and… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 117 REFERENCES

The biology of chromatin remodeling complexes.

  • Annual review of biochemistry
  • 2009
VIEW 13 EXCERPTS
HIGHLY INFLUENTIAL

A syntaxin 1, Galpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2004
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

Specificity, propagation, and memory of pericentric heterochromatin

  • Molecular systems biology
  • 2014
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

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