CHD1 regulates cell fate determination by activation of differentiation-induced genes

Abstract

The coordinated temporal and spatial activation of gene expression is essential for proper stem cell differentiation. The Chromodomain Helicase DNA-binding protein 1 (CHD1) is a chromatin remodeler closely associated with transcription and nucleosome turnover downstream of the transcriptional start site (TSS). In this study, we show that CHD1 is required… (More)
DOI: 10.1093/nar/gkx377

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