author={Setti S Rengachary and Chaim Colen and Murali Guthikonda},
BROWN-SÉQUARD IS known eponymously for the syndrome of hemisection of the spinal cord, but most clinicians are not familiar with his colorful, quixotic, and eccentric life history. His contributions to medicine and neuroscience reached much further than his discovery of the spinal hemisection syndrome. He lived in five countries on three continents and crossed the Atlantic 60 times, spending a total of almost 6 years on the sea. He contributed more than 500 papers in his lifetime, was even the… 
Brown-Séquard’s Famous Lecture that Gave Him the Eponym (and What Else He Said)
Key to Charles Edouard Brown-Séquard's work is a series of 12 lectures, in which he argues about many aspects of neurophysiology and spinal cord anatomy that led to his eponym.
The physician, the Emperor and the fibromyalgia: Charles-Édouard Brown-Séquard (1817–1894) and Dom Pedro II (1825–1891) of Brazil
The possibility that the Empress suffered from the fibromyalgia syndrome is raised, based on the exchange of letters between Dom Pedro II and Charles-Édouard Brown-Séquard, of considerable importance.
Traumatic Brown-Séquard syndrome: modern reminder of a neurological injury
This case presents the case of a man aged 38 years who sustained a stab injury to the left back and had an uneventful recovery to near baseline functional level after a course of rehabilitation.
Brown–Sequard described a rare, but important syndrome
The syndrome is described as follows: unilateral paralyses of voluntary motion below the level oflesion, ipsilateral hyperesthesia (observed only in animals); segmentalatrophy and sensory loss at thelevel of lesion; and contralateralanalgesia and thermanesthesia few segments below the lesion.
Brown-Sequard syndrome
A 67-year-old otherwise healthy woman was assaulted with a knife, receiving multiple stab wounds, and complained of weakness to her right upper and lower extremities.
Brown-Sequard syndrome after manual manipulation of the cervical spine: case report
This case highlights the benefit of swift surgical intervention followed by intensive inpatient rehab and serves as a warning for those who perform self-cervical manipulation.
Letters from Dom Pedro II to professor Brown-Séquard: imperial correspondence and neurophysiology.
The content of letters written by Dom Pedro II, the Emperor of Brazil, and sent to Doctor Charles Brown-Séquard, the famous neurologist, between 1876 and 1885 focuses mainly on his wife's, Princess Thereza Cristina, health issues and his personal desire to foster the research into the physiological study of the nervous system.


Historical perspective Brown-Sequard and his work on the spinal cord.
Brown-Sequard made many contributions to neurology, but is best known for his work on the sensory pathways in the spinal cord, which initially showed that these pathways are not confined to the posterior columns and that certain sensory fibers decussate soon after their entry into the spinal Cord.
Brown-Séquard: a visionary of science
Charles‐Edouard Brown‐Séquard: Double‐hyphenated Neurologist and Forgotten Father of Endocrinology
  • R. Tattersall
  • Medicine
    Diabetic medicine : a journal of the British Diabetic Association
  • 1994
This year is the Centenary of the death of Brown-Séquard who, although remembered today only for his eponymous syndrome, was as well known in the Victorian medical world as Robert Maxwell was to
Charles Edouard Brown-Séquard (1817-1894) *
The life of Brown-Sequard so approaches the fantastic in the ups and downs of his fortunes, in his incessant wanderings back and forth between two continents, in his prodigious, almost frenetic
Charles Édouard Brown‐Séquard
Brown-Séquard's career as Harvard's first professor of the physiology and pathology of the nervous system is chronicled in a unique and previously unpublished series of his private letters and
The Brown–Séquard and S. Weir Mitchell Letters
These letters, never before studied as a unit, provide insight into the men’s close collegial association in several domains and documents the views of two late nineteenth-century leaders in science and international academic medicine.
Brown-Séquard and cerebral localization as illustrated by his ideas on aphasia.
  • P. Koehler
  • Biology
    Journal of the history of the neurosciences
  • 1996
The origin and development of Brown-Séquard's ideas on aphasia from 1861 onwards are discussed, as is the part he possibly played in the transfer of knowledge from Paris to London (Broca and Jackson).
Brown-Séquard and the discovery of the vasoconstrictor nerves.
  • Y. Laporte
  • Biology, Medicine
    Journal of the history of the neurosciences
  • 1996
In August 1852, Brown-Séquard wrote a description of the effects he observed in various animals after electrical stimulation of the distal part of severed cervical sympathetic chains and concluded that the sympathetic chain sends motor nerve fibres to many of the blood vessels of the head and that vasodilation followed by hyperthermia resulted from the section of these fibres.
The Brown-Séquard and S
  • Weir Mitchell letters. Neurology 57:2100–2104,
  • 2001