CHARACTERIZATION OF THE INFLAMMATORY RESPONSE DURING ACUTE AND POST-ACUTE PHASES AFTER SEVERE BURN

@article{Gauglitz2008CHARACTERIZATIONOT,
  title={CHARACTERIZATION OF THE INFLAMMATORY RESPONSE DURING ACUTE AND POST-ACUTE PHASES AFTER SEVERE BURN},
  author={Gerd G. Gauglitz and Juquan Song and David N. Herndon and Celeste C. Finnerty and Darren Boehning and José Moreno Barral and Marc G. Jeschke},
  journal={Shock},
  year={2008},
  volume={30},
  pages={503-507}
}
Severe burn causes a pronounced hypermetabolic response characterized by catabolism and extensive protein wasting. We recently found that this hypermetabolic state is driven by a severe inflammatory response. We characterized in detail the kinetics of serum levels of a panel of cytokines in a rat model, which may serve as reference for the development of therapeutic interventions applicable to humans. Male Sprague-Dawley rats (n = 8) received a full-thickness burn of 60% total body surface area… 

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