CFTR channel insertion to the apical surface in rat duodenal villus epithelial cells is upregulated by VIP in vivo.

@article{Ameen1999CFTRCI,
  title={CFTR channel insertion to the apical surface in rat duodenal villus epithelial cells is upregulated by VIP in vivo.},
  author={Nadia A. Ameen and Bj{\"o}rn M{\aa}rtensson and L Bourguinon and Christopher C. Marino and Johannes Zander Tobias Isenberg and Gwenn E Mclaughlin},
  journal={Journal of cell science},
  year={1999},
  volume={112 ( Pt 6)},
  pages={887-94}
}
cAMP activated insertion of the cystic fibrosis transmembrane conductance regulator (CFTR) channels from endosomes to the apical plasma membrane has been hypothesized to regulate surface expression and CFTR function although the physiologic relevance of this remains unclear. We previously identified a subpopulation of small intestinal villus epithelial cells or CFTR high expressor (CHE) cells possessing very high levels of apical membrane CFTR in association with a prominent subapical vesicular… CONTINUE READING

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References

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Showing 1-10 of 44 references

The crypttovillus and crypttosurface epithelial cuff axes of the adult mouse gut represents an anatomically well - organized , continuous ‘ developmental ’ system

  • L. R. Johnson
  • Physiology of the Gastrointestinal Tract
  • 1994
Highly Influential
1 Excerpt

Role of microtubules in the rapid regulation of renal phosphate transport in response to acute alterations in dietary phosphate content

  • M. B. Lotscher, J. Kaissling, J. Biber, H. Murer, M. Levi
  • J . Clin . Invest .
  • 1997
2 Excerpts

CFTR-dependent membrane

  • J. Clin
  • 1996

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