CETP inhibitors and cardiovascular disease: Time to think again

@inproceedings{Miller2014CETPIA,
  title={CETP inhibitors and cardiovascular disease: Time to think again},
  author={Norman E. Miller and Cesare R. Sirtori and Gerald F. M. Watts},
  booktitle={F1000Research},
  year={2014}
}
Inhibition of cholesteryl ester transfer protein (CETP) lowers plasma low-density lipoprotein cholesterol concentration and raises high-density lipoprotein (HDL) cholesterol, suggesting it might prevent cardiovascular disease (CVD). From the outset, however, the concept has been controversial owing to uncertainty about its effects on HDL function and reverse cholesterol transport (RCT). Although there has long been good evidence that CETP inhibition reduces atherosclerosis in rabbits, the first… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 24 times over the past 90 days. VIEW TWEETS

References

Publications referenced by this paper.
Showing 1-10 of 11 references

Reviewing clinical trials: A guide for ethics committees

  • JPE Karlberg, MA Speers
  • 2010

Similar Papers

Loading similar papers…