CENP-E is a putative kinetochore motor that accumulates just before mitosis

@article{Yen1992CENPEIA,
  title={CENP-E is a putative kinetochore motor that accumulates just before mitosis},
  author={T. Yen and G. Li and B. Schaar and I. Szilak and D. Cleveland},
  journal={Nature},
  year={1992},
  volume={359},
  pages={536-539}
}
THE mechanics of chromosome movement, mitotic spindle assembly and spindle elongation have long been central questions of cell biology1. After attachment in prometaphase of a micro-tubule from one pole, duplicated chromosome pairs travel towards the pole in a rapid but discontinuous motion2,3. This is followed by a slower congression towards the midplate as the chromosome pair orients with each kinetochore attached to the microtubules from the nearest pole. The pairs disjoin at anaphase and… Expand
A new role for motor proteins as couplers to depolymerizing microtubules
Leaving no-one behind: how CENP-E facilitates chromosome alignment
The kinesin-like protein CENP-E is kinetochore-associated throughout poleward chromosome segregation during anaphase-A.
CENP-E Is a Plus End–Directed Kinetochore Motor Required for Metaphase Chromosome Alignment
Motor proteins in mitosis and meiosis
Anaphase A: Melting Microtubules Move Chromosomes toward Spindle Poles
CENP-E Function at Kinetochores Is Essential for Chromosome Alignment
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