CENP-B interacts with CENP-C domains containing Mif2 regions responsible for centromere localization.

@article{Suzuki2004CENPBIW,
  title={CENP-B interacts with CENP-C domains containing Mif2 regions responsible for centromere localization.},
  author={Nobutaka Suzuki and Megumi Nakano and Naohito Nozaki and Shin-ichiro Egashira and T. Okazaki and Hiroshi Masumoto},
  journal={The Journal of biological chemistry},
  year={2004},
  volume={279 7},
  pages={5934-46}
}
Recently, human artificial chromosomes featuring functional centromeres have been generated efficiently from naked synthetic alphoid DNA containing CENP-B boxes as a de novo mechanism in a human cultured cell line, but not from the synthetic alphoid DNA only containing mutations within CENP-B boxes, indicating that CENP-B has some functions in assembling centromere/kinetochore components on alphoid DNA. To investigate whether any interactions exist between CENP-B and the other centromere… CONTINUE READING
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