CELF Family RNA–Binding Protein UNC-75 Regulates Two Sets of Mutually Exclusive Exons of the unc-32 Gene in Neuron-Specific Manners in Caenorhabditis elegans

@inproceedings{Kuroyanagi2013CELFFR,
  title={CELF Family RNA–Binding Protein UNC-75 Regulates Two Sets of Mutually Exclusive Exons of the unc-32 Gene in Neuron-Specific Manners in Caenorhabditis elegans},
  author={Hidehito Kuroyanagi and Yohei Watanabe and Masatoshi Hagiwara},
  booktitle={PLoS genetics},
  year={2013}
}
An enormous number of alternative pre-mRNA splicing patterns in multicellular organisms are coordinately defined by a limited number of regulatory proteins and cis elements. Mutually exclusive alternative splicing should be strictly regulated and is a challenging model for elucidating regulation mechanisms. Here we provide models of the regulation of two sets of mutually exclusive exons, 4a-4c and 7a-7b, of the Caenorhabditis elegans uncoordinated (unc)-32 gene, encoding the a subunit of V0… CONTINUE READING
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Pre-mRNA splicing and its regulation in Caenorhabditis elegans.

WormBook : the online review of C. elegans biology • 2012
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