CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

Abstract

Engulfment of apoptotic cells in Caenorhabditis elegans is controlled by two partially redundant pathways. Mutations in genes in one of these pathways, defined by the genes ced-2, ced-5 and ced-10, result in defects both in the engulfment of dying cells and in the migrations of the two distal tip cells of the developing gonad. Here we find that ced-2 and… (More)
DOI: 10.1038/35004000

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@article{Reddien2000CED2CrkIIAC, title={CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans}, author={Peter W Reddien and H. Robert Horvitz}, journal={Nature Cell Biology}, year={2000}, volume={2}, pages={131-136} }