CEACAM1: contact-dependent control of immunity
@article{GrayOwen2006CEACAM1CC, title={CEACAM1: contact-dependent control of immunity}, author={Scott D. Gray-Owen and Richard S. Blumberg}, journal={Nature Reviews Immunology}, year={2006}, volume={6}, pages={433-446} }
The carcinoembryonic-antigen-related cell-adhesion molecule (CEACAM) family of proteins has been implicated in various intercellular-adhesion and intracellular-signalling-mediated effects that govern the growth and differentiation of normal and cancerous cells. Recent studies show that there is an important role for members of the CEACAM family in modulating the immune responses associated with infection, inflammation and cancer. In this Review, we consider the evidence for CEACAM involvement…
458 Citations
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