CEACAM1/VEGF cross-talk during neuroblastic tumour differentiation.

  title={CEACAM1/VEGF cross-talk during neuroblastic tumour differentiation.},
  author={Pietro Luigi Poliani and Stefania Mitola and Maria Ravanini and Giulia Ferrari-Toninelli and Cristina D'ippolito and Luigi D Notarangelo and Luisa Bercich and Christoph Wagener and Maurizio Memo and Marco Presta and Fabio F. Facchetti},
  journal={The Journal of pathology},
  volume={211 5},
The role of angiogenesis in tumour progression is a major subject in modern oncology and a correlation between angiogenesis and poor outcome has been demonstrated for human neuroblastomas. However, the role of angiogenesis in the maturation phase of neuroblastic tumours has never been considered. Human carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), a potent pro-angiogenic factor and mediator of vascular endothelial growth factor (VEGF)-induced angiogenesis, plays a crucial… CONTINUE READING

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