CDP-choline at high doses is as effective as i.v. thrombolysis in experimental animal stroke.

Abstract

Use of thrombolysis in acute ischaemic stroke may be limited by a narrow benefit/risk ratio. Pharmacological inhibition of the ischaemic cascade may constitute an effective and safer approach to stroke treatment. This study compared the effects of high doses of cytidine diphosphate-choline (CDP-choline; 1000 mg/kg) with recombinant tissue plasminogen… (More)
DOI: 10.1179/1743132812Y.0000000058

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