CDK6 associates with the centrosome during mitosis and is mutated in a large Pakistani family with primary microcephaly.

Abstract

Autosomal recessive primary microcephaly (MCPH) is characterized by reduced head circumference, reduction in the size of the cerebral cortex with otherwise grossly normal brain structure and variable intellectual disability. MCPH is caused by mutations of 11 different genes which code for proteins implicated in cell division and cell cycle regulation. We… (More)
DOI: 10.1093/hmg/ddt374

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