CDDO-Me protects against space radiation-induced transformation of human colon epithelial cells.

@article{Eskiocak2010CDDOMePA,
  title={CDDO-Me protects against space radiation-induced transformation of human colon epithelial cells.},
  author={Ugur Eskiocak and Sang Bum Kim and Andres I. Roig and Erin Kitten and Kimberly G. Batten and Crystal Cornelius and Ying S. Zou and Woodring E Wright and Jerry W Shay},
  journal={Radiation research},
  year={2010},
  volume={174 1},
  pages={27-36}
}
Radiation-induced carcinogenesis is a major concern both for astronauts on long-term space missions and for cancer patients being treated with therapeutic radiation. Exposure to radiation induces oxidative stress and chronic inflammation, which are critical initiators and promoters of carcinogenesis. Many studies have demonstrated that non-steroidal anti-inflammatory drugs and antioxidants can reduce the risk of radiation-induced cancer. In this study, we found that a synthetic triterpenoid… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 16 extracted citations

Similar Papers

Loading similar papers…