CDD: specific functional annotation with the Conserved Domain Database

  title={CDD: specific functional annotation with the Conserved Domain Database},
  author={Aron Marchler-Bauer and John B. Anderson and Farideh Chitsaz and Myra K. Derbyshire and Carol DeWeese-Scott and Jessica H. Fong and Lewis Y. Geer and Renata C. Geer and Noreen R. Gonzales and Marc Gwadz and Siqian He and David I. Hurwitz and John D. Jackson and Zhaoxi Ke and Christopher J. Lanczycki and Cynthia A. Liebert and Chunlei Liu and Fu Lu and Shennan Lu and Gabriele H. Marchler and Mikhail Mullokandov and James S. Song and Asba Tasneem and Narmada Thanki and Roxanne A. Yamashita and Dachuan Zhang and Naigong Zhang and Stephen H. Bryant},
  booktitle={Nucleic Acids Research},
NCBI's Conserved Domain Database (CDD) is a collection of multiple sequence alignments and derived database search models, which represent protein domains conserved in molecular evolution. The collection can be accessed at, and is also part of NCBI's Entrez query and retrieval system, cross-linked to numerous other resources. CDD provides annotation of domain footprints and conserved functional sites on protein sequences. Precalculated domain… CONTINUE READING
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