CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae

@article{Adams1990CDC42AC,
  title={CDC42 and CDC43, two additional genes involved in budding and the establishment of cell polarity in the yeast Saccharomyces cerevisiae},
  author={Alison E. M. Adams and Douglas I. Johnson and Richard Longnecker and B F Sloat and John R. Pringle},
  journal={The Journal of Cell Biology},
  year={1990},
  volume={111},
  pages={131 - 142}
}
Budding in the yeast Saccharomyces cerevisiae involves a polarized deposition of new cell surface material that is associated with a highly asymmetric disposition of the actin cytoskeleton. Mutants defective in gene CDC24, which are unable to bud or establish cell polarity, have been of great interest with regard to both the mechanisms of cellular morphogenesis and the mechanisms that coordinate cell-cycle events. To gain further insights into these problems, we sought additional mutants with… CONTINUE READING
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