CD97, but not its closely related EGF-TM7 family member EMR2, is expressed on gastric, pancreatic, and esophageal carcinomas.

@article{Aust2002CD97BN,
  title={CD97, but not its closely related EGF-TM7 family member EMR2, is expressed on gastric, pancreatic, and esophageal carcinomas.},
  author={Gabriela Aust and Matthias Steinert and Alexander Sch{\"u}tz and Carsten Boltze and Mandy Wahlbuhl and Joerg Hamann and Manja Wobus},
  journal={American journal of clinical pathology},
  year={2002},
  volume={118 5},
  pages={699-707}
}
CD97 expression is related closely to the dedifferentiation and tumor stage in thyroid carcinomas. We systematically examined the role of CD97 and its closest relative, EMR2, in normal and malignant gastric, esophageal, and pancreatic tissue. The normal tissues were EMR2-, whereas CD97 was expressed slightly in the parietal cells of gastric mucosa and in exocrine pancreatic cells. Interestingly, intralobular and interlobular pancreatic ducts were CD97+. All tumors were EMR2-. CD97 was expressed… CONTINUE READING

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