CD91: a receptor for heat shock protein gp96

@article{Binder2000CD91AR,
  title={CD91: a receptor for heat shock protein gp96},
  author={Robert Julian Binder and David K. Han and Pramod K. Srivastava},
  journal={Nature Immunology},
  year={2000},
  volume={1},
  pages={151-155}
}
Antigen presenting cells (APCs) can take up exogenous antigenic peptides chaperoned by heat shock protein gp96 and re-present them through the endogenous pathway on their major histocompatibility class I molecules. The high efficiency of this process has been attributed previously to a receptor for gp96 on APCs. The CD91 molecule (also called α2… CONTINUE READING