CD90/THY1 is over-expressed in prostate cancer-associated fibroblasts and could serve as a cancer biomarker

@inproceedings{True2010CD90THY1IO,
  title={CD90/THY1 is over-expressed in prostate cancer-associated fibroblasts and could serve as a cancer biomarker},
  author={Lawrence D. True and Hui Zhang and Mingliang Ye and Chung-Ying Huang and Peter S. Nelson and Priska D. von Haller and Larry W. Tjoelker and Jong-Seo Kim and Wei-Jun Qian and Richard D. Smith and W. J. Ellis and Emily S. Liebeskind and Alvin Y. Liu},
  booktitle={Modern Pathology},
  year={2010}
}
A by-product in the processing of prostate tissue for cell sorting by collagenase digestion is the media supernatant that remains after the cells are harvested. These supernatants contain proteins made by the cells within the tissue. Quantitative proteomic analysis of N-glycosylated proteins detected an increased amount of CD90/THY1 in cancer supernatants compared with non-cancer supernatants. Immunohistochemistry showed that in all carcinomas, regardless of Gleason grade, a layer of CD90… CONTINUE READING
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