CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2.

@article{Tangye2002CD84IU,
  title={CD84 is up-regulated on a major population of human memory B cells and recruits the SH2 domain containing proteins SAP and EAT-2.},
  author={Stuart G Tangye and Barbara C M van de Weerdt and Danielle T Avery and Philip D. Hodgkin},
  journal={European journal of immunology},
  year={2002},
  volume={32 6},
  pages={
          1640-9
        }
}
CD84 is a member of the CD2 subset of the immunoglobulin superfamily of cell surface receptors. Several members of this family are involved in the activation of T cells and NK cells. Although CD84 was originally cloned from a human B cell line cDNA library, very little is known regarding its biology on primary human leukocytes. We investigated the expression and biochemistry of CD84 on human B cells. CD84 was expressed on B cells in peripheral blood, spleen and cord blood. Two populations of… CONTINUE READING
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