CD81-Receptor Associations — Impact for Hepatitis C Virus Entry and Antiviral Therapies

@inproceedings{Zona2014CD81ReceptorA,
  title={CD81-Receptor Associations — Impact for Hepatitis C Virus Entry and Antiviral Therapies},
  author={Laetitia Zona and Rajiv G. Tawar and Mirjam B Zeisel and Catherine Schuster and Joachim Lupberger and Thomas F Baumert},
  booktitle={Viruses},
  year={2014}
}
Tetraspanins are integral transmembrane proteins organized in microdomains displaying specific and direct interactions with other tetraspanins and molecular partners. Among them, CD81 has been implicated in a variety of physiological and pathological processes. CD81 also plays a crucial role in pathogen entry into host cells, including hepatitis C virus (HCV) entry into hepatocytes. HCV is a major cause of liver cirrhosis and hepatocellular carcinoma. HCV entry into hepatocytes is a complex… CONTINUE READING

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Tetraspanin Assemblies in Virus Infection

  • Front. Immunol.
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