CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance

@article{CaraFuentes2013CD80AS,
  title={CD80 and suPAR in patients with minimal change disease and focal segmental glomerulosclerosis: diagnostic and pathogenic significance},
  author={Gabriel Cara-Fuentes and Changli Wei and Alfons Segarra and Takuji Ishimoto and Christopher J. Rivard and Richard J Johnson and Jochen Reiser and Eduardo H Garin},
  journal={Pediatric Nephrology},
  year={2013},
  volume={29},
  pages={1363-1371}
}
Minimal change disease (MCD) is characterized by increased urinary excretion of CD80, whereas focal segmental glomerulosclerosis (FSGS) is associated with increased serum soluble urokinase-type plasminogen activator receptor (suPAR). The aim of the study was to assess whether the simultaneous measurement of urinary CD80 and serum suPAR helps differentiate MCD and FSGS. Urine and sera were collected from patients with MCD in relapse or in remission, from FSGS patients with nephrotic syndrome… CONTINUE READING
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