CD8+ memory T lymphocytes from bone marrow--immune function and therapeutic potential.

@article{Wood2007CD8MT,
  title={CD8+ memory T lymphocytes from bone marrow--immune function and therapeutic potential.},
  author={Aaron H D Wood and Xiaoyu Zhang and Donna L Farber and Scott E. Strome},
  journal={Critical reviews in immunology},
  year={2007},
  volume={27 6},
  pages={527-37}
}
Immunity to previously encountered diseases is provided in large part by memory T lymphocytes, which may be subdivided based on phenotypic and functional differences, as well as the specific cellular compartments in which these cells reside. The bone marrow (BM) is a unique microenvironment that supports robust proliferation and recall responses of both "central" and "effector" memory T cells, particularly within the CD8+ T cell subset. The recent identification within human BM of a population… CONTINUE READING
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