CD8+ T cells in cutaneous leishmaniasis: the good, the bad, and the ugly

@article{Novais2015CD8TC,
  title={CD8+ T cells in cutaneous leishmaniasis: the good, the bad, and the ugly},
  author={Fernanda O. Novais and Phillip Scott},
  journal={Seminars in Immunopathology},
  year={2015},
  volume={37},
  pages={251-259}
}
CD8+ T lymphocytes are components of the adaptive immune response and play an important role in protection against many viral and bacterial infections. However, their role in parasitic infections is less well understood. In leishmaniasis, a disease caused by intracellular protozoan parasites of the genus Leishmania, CD8+ T cells have been shown to be protective. However, increasing evidence indicates that CD8+ T cells may also exacerbate disease. In this review, we will describe the situations… CONTINUE READING
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