CD8+ T cells in Trypanosoma cruzi infection

  title={CD8+ T cells in Trypanosoma cruzi infection},
  author={Rick L. Tarleton},
  journal={Seminars in Immunopathology},
Trypanosoma cruzi infection and Chagas disease remains among the most neglected of the neglected tropical diseases. Despite this, studies of the immune response to T. cruzi have provided new insights in immunology and guidance for approaches for prevention and treatment of the disease. T. cruzi represents one of the very best systems in which to study CD8+ T cell biology; mice, dogs, and primates (and many other mammals) are all natural hosts for this parasite, the robust T cell responses… CONTINUE READING
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