CD8+ T cell tolerance following antigen recognition on hepatocytes.

Abstract

Hepatocytes, the predominant cell type in the liver, are the main cell infected by the hepatitis C virus (HCV) and represent important targets for immune therapy. Although early studies suggested that this parenchymal cell expresses low levels of class I MHC molecules, hepatocytes are emerging as important players in intrahepatic immune responses. Not only… (More)
DOI: 10.1016/j.jaut.2009.08.005

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