CD8+ T-cell responses to different HIV proteins have discordant associations with viral load


Selection of T-cell vaccine antigens for chronic persistent viral infections has been largely empirical. To define the relationship, at the population level, between the specificity of the cellular immune response and viral control for a relevant human pathogen, we performed a comprehensive analysis of the 160 dominant CD8+ T-cell responses in 578 untreated… (More)
DOI: 10.1038/nm1520


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