CD74 is a survival receptor on colon epithelial cells.

@article{Maharshak2010CD74IA,
  title={CD74 is a survival receptor on colon epithelial cells.},
  author={Nitsan Maharshak and Sivan Cohen and Frida Lantner and G Hart and L. Lim Biaw Leng and Richard J Bucala and Idit Shachar},
  journal={World journal of gastroenterology},
  year={2010},
  volume={16 26},
  pages={
          3258-66
        }
}
AIM To investigate the expression and function of CD74 in normal murine colon epithelial cells (CEC) and colon carcinoma cells. METHODS Expression of CD74 mRNA and protein were measured by reverse transcriptase-polymerase chain reaction (RT-PCR), Western blotting and fluorescence-activated cell sorter (FACS). The effect of migration inhibitory factor (MIF) on the survival of normal CEC from C57BL/6, NOD/SCID, and CD74 deficient mice both in vitro and in vivo, and on the CT26 carcinoma cell… CONTINUE READING

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