CD73 expression and fyn-dependent signaling on murine lymphocytes.

@article{Yamashita1998CD73EA,
  title={CD73 expression and fyn-dependent signaling on murine lymphocytes.},
  author={Yoshio Yamashita and Scott W. Hooker and Hong Jiang and Aletha B Laurent and Regina Resta and Kedar Khare and Allison Coe and Paul W. Kincade and Linda F. Thompson},
  journal={European journal of immunology},
  year={1998},
  volume={28 10},
  pages={2981-90}
}
CD73 is a glycosyl phosphatidylinositol-anchored protein with both ecto-enzyme activity (ecto-5'-nucleotidase) and signal transducing capabilities for human T lymphocytes. We now report an analysis of the distribution and function of CD73 in murine lymphoid tissues made possible by the development of the first monoclonal antibodies (mAb) specific for murine CD73. Subsets of T and B lymphocytes are CD73+ and the level of expression increases with lymphocyte maturation in both species. Among B… CONTINUE READING