CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta

@article{Moretta1991CD69mediatedPO,
  title={CD69-mediated pathway of lymphocyte activation: anti-CD69 monoclonal antibodies trigger the cytolytic activity of different lymphoid effector cells with the exception of cytolytic T lymphocytes expressing T cell receptor alpha/beta},
  author={Alessandro Moretta and Alessandro Poggi and Daniela Pende and G. D. Tripodi and Anna Maria Orengo and Nicoletta Pella and Raffaella Augugliaro and Cristina Bottino and Ermanno Ciccone},
  journal={The Journal of Experimental Medicine},
  year={1991},
  volume={174},
  pages={1393 - 1398}
}
The effect of anti-CD69 monoclonal antibodies (mAbs) on the induction of the cytolytic activity in different types of lymphoid effector cells has been investigated. Three anti-CD69 mAbs, including the reference mAb MLR3 and two new mAbs (c227 and 31C4), have been used. All cloned CD3-CD16+ natural killer (NK) cells belonging to different subsets (as defined by the surface expression of GL183 and/or EB6 antigens) were efficiently triggered by anti-CD69 mAbs and lysed P815 mastocytoma cells in a… CONTINUE READING

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References

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Showing 1-10 of 30 references

Functional and biochemical characterization of the activation CD69 antigen defined by A40 (MLR3) mAb

M. E. Cosulich, A. Risso, +7 authors A. Bargellesi
Leucocyte Typing IV : White Cell Differentiation Antigens . • 1989
View 13 Excerpts
Highly Influenced

T cell activation via Leu-23 (CD69).

Journal of immunology • 1989
View 4 Excerpts
Highly Influenced

Definition of the thymic generative lineage by selective expression of high molecular weight isoforms of CD 45 ( T 200 )

M. C. Mingari
Eur . J . Immunol • 1989

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