CD66b overexpression and homotypic aggregation of human peripheral blood neutrophils after activation by a gram-positive stimulus.

@article{Schmidt2012CD66bOA,
  title={CD66b overexpression and homotypic aggregation of human peripheral blood neutrophils after activation by a gram-positive stimulus.},
  author={Thomas H. Schmidt and Josef Z{\"u}ndorf and Thomas Grueger and Kerstin Brandenburg and Ana-Lena Reiners and Joerg Zinserling and N. Elsner H.-U. Schnitzler},
  journal={Journal of leukocyte biology},
  year={2012},
  volume={91 5},
  pages={
          791-802
        }
}
Neutrophils represent the main component of innate immunity in the clearance of bacterial infections. To pass the tissue and to localize and reach the site of infection, the peripheral blood neutrophils have to pass through a complex receptor-mediated interaction with the endothelial layer. Under pathophysiological conditions, such as severe sepsis, this process is impaired and often characterized by neutrophil aggregation. In this study, we examined the impact of three different Staphylococcus… CONTINUE READING
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