CD66a, CD66b, CD66c, and CD66d each Independently stimulate neutrophils

  title={CD66a, CD66b, CD66c, and CD66d each Independently stimulate neutrophils},
  author={K. Skubitz and K. D. Campbell and A. P. Skubitz},
  journal={Journal of Leukocyte Biology},
  • K. Skubitz, K. D. Campbell, A. P. Skubitz
  • Published 1996
  • Biology, Medicine
  • Journal of Leukocyte Biology
  • Four members of the earcinoembryonic antigen family, CD66a, CD66b, CD66c, and CD66d, are expressed on human neutrophils. In neutrophils these proteins are activation antigens in that their surface expression is increased following stimulation. To examine their potential role in neutrophil signaling, the effects on neutrophil adhesion to human umbilical vein endothelial cells of a panel of well‐characterized CD66 mAbs was tested. CD66a, CD66b, CD66c, and CD66d antibodies each increased… CONTINUE READING
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