CD57+ T lymphocytes and functional immune deficiency.

  title={CD57+ T lymphocytes and functional immune deficiency.},
  author={Daniele Focosi and Marco Bestagno and Oscar R Burrone and Mario Petrini},
  journal={Journal of leukocyte biology},
  volume={87 1},
CD57(+) expression in T lymphocytes has been recognized for decades as a marker of in vitro replicative senescence. In recent years, accumulating evidences have pointed on the utility of this marker to measure functional immune deficiency in patients with autoimmune disease, infectious diseases, and cancers. We review here the relevant literature and implications in clinical settings. 
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